FACT: Scientists Restore Vision Without Surgery In Animal Studies

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By Victor Olubiye


A team from the Korea Advanced Institute of Science and Technology (KAIST) has taken a major step forward in vision loss research. They successfully regenerated nerve cells in the retina of mammals without surgery, using an experimental treatment that could change the future of diseases like retinitis pigmentosa and macular degeneration.

 How does it work?

Researchers discovered that a protein called PROX1 blocks the natural regeneration of retinal cells. By using a special antibody (CLZ001), they were able to deactivate this protein, allowing glial cells to transform into new neurons.

In tests with mice suffering from vision loss, sustained visual recovery was observed for more than 6 months.

While this therapy is not yet available for humans, it represents real hope for millions living with blindness or degenerative eye diseases.


 Clinical trials are expected to begin in 2028.


Source: Nature Communications, via KAIST.

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